In the new development, men may soon be able to fairly share responsibility for avoiding pregnancy, along with their partners like YCT-529, an experimental contraceptive pill underwent an initial human safety test, which caused another way of contraception. Reportedly temporarily stops sperm without defending hormones.
What is yct-529?
Unlike conventional pills with hormonal contraceptives, an innovative pill has developed a temporarily stopping sperm production at the unchanged testosterone level, New York Post reported.
It works by inhibiting a receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor receptor recept Completely reversible.
In tests including YCT-529, sperm production significantly reduced, leading to reversible infertility after only four weeks of treatment. When they treated men kept by women, the drug showed 99% success in preventing pregnancy.
Comparable results were observed in male non -luminous primates, while the number of sperm decreases within two weeks of starting treatment. Importantly, fertility has been fully restored in both species as soon as the drug has been interrupted. The mice recovered within six weeks, while the primates regained fertility between 10 and 15 weeks. There were no side effects in any group in the studies, she added a message.
The initial human drug test included 16 healthy men aged 32 to 59 years, all of whom had previously had vasectomy, a surgery that slashes and blocks the tubes carrying sperm from the testicles to prevent conception.
This additional security measure was required because no non -hormonal male contraception has never been evaluated in humans. Scientists wanted to eliminate any chance of a lasting impact on fertility, if the participants wanted to have children later, Nadja Mannowetz, co -founder and chief scientific director of Yourchoice Therapeutics, informed.
She explained that the aim was not to assess the efficiency, but to find out if the drug was well tolerated and observed as the body accumulates.
Human Safety YCT-529
Scientists have tested more doses and found that they concern side effects. No changes in heart rate, hormone levels, inflammation, sexual function or mood were found.
This finding is important because hormonal contraceptives were previously associated with side effects such as mood swings, reduced libido, weight gain and acne. Mannowetz pointed out that at all doses the drug showed good and rapid biological availability, which means that it remained active in the body without breaking down too quickly.
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