American tech entrepreneur and anti-aging influencer Bryan Johnson – best known for spending millions annually to reverse his biological age – has now experimented with magic mushrooms as part of his longevity research.
Johnson, who runs anti-aging startup Blueprint, revealed on social media that he took a five-gram dose of the psychedelic substance in an effort to study its potential effects on longevity and brain function. The 46-year-old shared his experience on X (formerly Twitter), writing: “Yes, this trip has changed me. Probably not in the way you’d expect. People assume I’m afraid of death. I’m not. In my darkest days of depression, I came to terms with death.” He added that he needed a few days to collect his thoughts before sharing more experiences.
The businessman described feeling “so happy to be alive” during the trip, later writing, “Life is fresh today. New ideas are flowing. My mind feels more nimble and curious.” He also continued his strict daily routine – which includes early morning exposure to light, a nutritious breakfast, exercise, sauna and red light therapy – along with undergoing tests such as brain scans and blood analysis.
Before the experiment, Johnson said he planned to take the psychedelic once a month for three months to evaluate its “longevity effects.” His tests would measure biological markers such as DNA integrity, cellular aging, protein levels, metabolism and brain activity.
During the session, Johnson’s co-founder Kate Tolo took over his social media accounts and documented the process as a “trip-sitter.”
About Bryan Johnson
Johnson, who made his fortune after selling his payments company to eBay in his 30s, spends nearly $2 million a year on medical diagnostics, therapies and lifestyle interventions to slow aging. His antiaging protocol—which includes a precise diet, sleep schedule, and more than 100 daily supplements—has made him a controversial but fascinating figure in the wellness and tech communities.
The influencer continues to test new methods to push the limits of human longevity, and his latest experiment with psychedelics has sparked debate among biohackers and scientists alike.
